420 Dayton

420 Dayton Ohio's First Cannabis Friendly Park! Bringing together community, entertainment and small businesses in a cannabis friendly place!

Join us for good vibes and great times.

The Halloween decorating committee is meeting to discuss ideas for the park this year! The ideas are just flowing 😂💀
09/16/2026

The Halloween decorating committee is meeting to discuss ideas for the park this year! The ideas are just flowing 😂💀

09/10/2026

Need some recommendations! We need a landscaper that can do lawncare, brush removal, concrete work, yard drainage clean out and flowerbed planting and mulching! If you have anyone who's dependable and does good work please let us know in the comments below! Thank you!!

👀 THERE’S SOMETHING WE CAN’T TELL YOU ON FACEBOOK…We’ve got a little surprise going on with Cannabuyit delivery, but Fac...
09/10/2026

👀 THERE’S SOMETHING WE CAN’T TELL YOU ON FACEBOOK…

We’ve got a little surprise going on with Cannabuyit delivery, but Facebook and our announcements don’t exactly get along. 😂

So we’ll just say this:

🚗 If you use Cannabuyit delivery, you’re going to want to know about this one.

🎁 There’s a surprise involved.

That’s all we’re saying here. 🤐

👉 Check the Announcements section on our website for the details:

Welcome to Cannabuyit, Dayton’s Recreational Dispensary! Browse premium flower, concentrates, edibles, pre-rolls, and more from one of Dayton’s most trusted recreational cannabis destinations. Shop online or stop by and see what’s new. Shop Now 📣 Announcements 📣 August 13, 20262 NEW SALE...

Starting to look a little more festive at the park! Have you been by to see the new decorations? 🎃  ✨️Things are changin...
09/09/2026

Starting to look a little more festive at the park! Have you been by to see the new decorations?
🎃 ✨️Things are changing ✨️ 🎃

09/08/2026

Good morning! Website is back online! We will be open at 11am! We hope you're all rested and enjoyed your long weekend and we can't wait to see you at the park! Have a great day!

09/07/2026

Happy Labor day!!! We are closed today and we will be back open tomorrow at 11am! We hope you all have a great holiday! We will see you tomorrow!

09/06/2026
420 Dayton and Cannabuyit Dayton will be closed Monday for Labor Day! We hope you all have a fantastic holiday weekend! ...
09/05/2026

420 Dayton and Cannabuyit Dayton will be closed Monday for Labor Day! We hope you all have a fantastic holiday weekend! Be careful, get some rest and relaxation and we will see you Tuesday!!!! Happy Labor Day!!

Has anyone had issues with the website? If so please let us know in the comments below! Thank you!!!
09/04/2026

Has anyone had issues with the website? If so please let us know in the comments below! Thank you!!!

Welcome to Cannabuyit, Dayton’s Recreational Dispensary! Browse premium flower, concentrates, edibles, pre-rolls, and more from one of Dayton’s most trusted recreational cannabis destinations. Shop online or stop by and see what’s new. Shop Now 📣 Announcements 📣 August 13, 20262 NEW SALE...

09/02/2026

Modern oncology may be moving beyond the traditional strategy of simply poisoning cancer cells, shifting toward a far more elegant approach: permanently disarming their ability to spread. A landmark study reveals that briefly activating a natural cellular switch, known as cannabinoid receptor 2 (CB2R), can lock aggressive breast cancer cells into a stable, non-invasive state.

The primary danger of breast cancer stems from the remarkable shape-shifting ability of malignant cells. When aggressive tumour cells revert into primitive, stem-like states, they easily detach, migrate to distant organs and resist conventional chemotherapy. While standard treatments focus on destroying these cells through brute chemical force—which often inadvertently selects for the most resilient survivors—researchers explored whether rogue cells could instead be reprogrammed into harmless, mature tissue.

By delivering a brief signal to the CB2R pathway naturally present on cell membranes, scientists triggered a comprehensive genetic reset. The treatment coaxed flexible, high-risk cancer cells to mature into stable luminal cells, effectively stripping them of their migratory instincts and tumour-forming potential.

The most encouraging discovery is the permanence of this transformation. Even long after the molecular trigger was removed, the cancer cells remembered their new, stable identity. They resisted environmental cues that normally induce metastasis and lost their invasive drive entirely. Furthermore, adopting this mature profile resensitised the cells to established hormone therapies like tamoxifen, paving the way for safer, lower-dose combination treatments.

This transition from cellular destruction to cellular reprogramming represents a major step forward in cancer research, pointing toward future therapies that safely neutralise tumours without subjecting the body to severe toxicity.

Transient CB2R Modulation Durably Restricts Breast Cancer Plasticity by Stabilising a Luminal Like Cell Identity | https://zenodo.org/records/21457626

Address

1040 East First Street
Dayton, OH
45402

Opening Hours

Monday 11am - 7pm
Tuesday 11am - 7pm
Wednesday 11am - 7pm
Thursday 11am - 7pm
Friday 11am - 7pm
Saturday 11am - 7pm

Telephone

+19375421232

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