The Guadalupe on Main

The Guadalupe on Main Family owned modern southwest cusine with flavors from Jalisco Mexico. Craft cocktails and mixology is our specialty.
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Relaxing and colorful atmosphere will make it hard to leave.

09/03/2026

Ground Beef Tacos Dorados 🌮
This weekend only 2 tacos + rice & beans $14

1/2 Price Wings Every WednesdayFlavors Include-Korean Red-Brown Butter Piloncillo Chile de Arbol-Garlic Cilantro Mojo ...
09/02/2026

1/2 Price Wings Every Wednesday
Flavors Include
-Korean Red
-Brown Butter Piloncillo Chile de Arbol
-Garlic Cilantro Mojo
wings

08/30/2026

🍸 GUEST BARTENDER ALERT! 🍸
We’re extremely excited to announce that Christian Bergman will be taking over the bar at The Guadalupe on Main for a special guest bartending shift on Wednesday, September 9th! 🌵🔥
Come hang out, grab a cocktail, and watch Christian do what he does best. 🍹
⏰ Exact hours will be announced soon — stay tuned!
Can’t wait until September 9th? Go catch Christian behind the bar at Best martinis in Arizona in Old Town Scottsdale!
🌮 Normal dinner service will continue as usual.
🍸 Bar seating will be first come, first served — no reservations for the bar.
Mark your calendars. September 9th is going to be a fun one. 🔥

🔥 NEW CHEF’S SPECIALS ARE HERE 🔥And Chef Jhomeny is putting his spin on pork belly tacosCrispy pork belly + avocado crem...
08/21/2026

🔥 NEW CHEF’S SPECIALS ARE HERE 🔥

And Chef Jhomeny is putting his spin on pork belly tacos

Crispy pork belly + avocado crema + tamarindo glaze + pickled red onion + cilantro + salsa macha crumble, all tucked into fresh 50/50 blue & yellow corn tortillas

Plus, the return of our crispy breaded wings with a new Korean Red sauce and an Ube Cookie Skillet for dessert.
Because one course is never enough. 😉

Swipe ➡️ to see Chef bring those tacos to life.

Chef’s Specials | Available while supplies last

This Thursday August 20thMusic Bingo returns from 7-9pmHosted by ColbyFREE TO PLAY
08/17/2026

This Thursday August 20th
Music Bingo returns from 7-9pm
Hosted by Colby
FREE TO PLAY

1/2 price wings on Wednesdays!
08/12/2026

1/2 price wings on Wednesdays!

Chef's Specials | 8/5–8/9The people have spoken... so wings are back for another week! Choose your sauce: 🔥 Brown Butter...
08/06/2026

Chef's Specials | 8/5–8/9

The people have spoken... so wings are back for another week!
Choose your sauce: 🔥 Brown Butter Piloncillo Chile de Árbol 🌿 Garlic Cilantro Mojo 🤎 Mole

New this week: Chef Jhomeny's Tacos al Pastor and Coconut Flan (dairy free)

Chef's Specials are available while supplies last

Which one are you trying first?

07/31/2026

🚨 This weekend only 🚨
We would like to thank everyone that voted for our chef Jhomeny Ramos in PHOENIX magazine best of the valley readers choice!
This weekend we will be celebrating by giving away 1 free order of our gluten free churros per table!
All you have to do is like, comment, & reshare this post!
Show your server or bartender the video when ordering & we will take care of the churros.
Must be following us on instagram to receive the free order. 1 order per table.
Awards we took home
Phoenix Magazine
-Best Chef - 2026
-Best Mexican Restaurant - 2025/2026
-Best New Restaurant - 2025
AZ New Times
-Best Margaritas- 2025

Join us August 10th to watch our latest bartender battle.
07/25/2026

Join us August 10th to watch our latest bartender battle.

Address

1526 E Main Street
Mesa, AZ
85204

Opening Hours

Wednesday 11am - 10pm
Thursday 11am - 10pm
Friday 11am - 11pm
Saturday 11am - 11pm
Sunday 11am - 9pm

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