Call Directions Website Contact the establishment

Elixir Award-winning, historic saloon, open 365, with a sun-lit Happy Hour, craft cocktails, 600+ whiskeys, sports on tv and friendly, knowledgeable bartenders.
(367)

ELIXIR, The Exceptional Neighborhood Saloon, is located in the Mission Dolores section of San Francisco, on the corner of 16th Street and Guerrero, where it has served its neighbors since at least 1858. Pouring fresh and diverse draft beer, wine and cocktails, and mixing unique, hand-made cocktails with fresh produce distinguishes Elixir from the numerous bars in this vibrant nightlife corridor. As the Second Oldest Saloon location in the city, it is an authentic piece of the Old West that combines the warm appeal of a contemporary Pub, the camaraderie of a Sports Bar and the sultry allure of a Cocktail Lounge. Elixir morphs on a daily basis from a boisterous and sun-lit 4-Hour Happy Hour to a velvet-curtained and candle-lit nightlife. Early week programs include Monday's Bingo Night, Tuesday's Elixir Quiz, Wednesday's Charity Guest Bartending and Thursday's Cocktail Club. From real dartboards and an internet jukebox, to theme nights and friendly bartenders, Elixir is a comfortable neighborhood bar with a great vibe.

Which are your favorites? These are some of the best selling original recipes at Elixir over the last couple of decades....
10/23/2026

Which are your favorites? These are some of the best selling original recipes at Elixir over the last couple of decades. Cube grab them now, because as of 11/1, we're getting out holiday spirit on! Get ready for the nog!

10/20/2026

Game time 5pm. Sound on. Elixir Quiz at 7
The Shield Maiden
Butterfly Pea Tea-infused, Norcal-made Charbay vodka, Green Chartreuse, Giffard Pamplemousse, Fresh Victor Lemon Sour, soda water, lemon shield

10/06/2026

How San Francisco bars, such as Elixir and Bourbon and Branch, have stood the test of time.

📸 Mark Mediana

A guide to influential San Francisco cocktail bars like Elixir and Bourbon & Branch that have stood the test of time.

THE BAD NEWS: We will be closed tomorrow night for a private wh**ky event. THE GOOD NEWS: Maybe you can snag a seat.
10/06/2026

THE BAD NEWS: We will be closed tomorrow night for a private wh**ky event. THE GOOD NEWS: Maybe you can snag a seat.

10/05/2026
Thank you to everyone who joined us for the 2nd annual Bourbon Festival. Enjoy these!
10/05/2026

Thank you to everyone who joined us for the 2nd annual Bourbon Festival. Enjoy these!

We're super excited to announce this new partnership with two of the finest premium spirits shops in San Francisco: D& M...
10/02/2026

We're super excited to announce this new partnership with two of the finest premium spirits shops in San Francisco: D& M Liquors and London Market! Read on...

It happens on the first Monday of every month from 7:00 p.m. to 9:00 p.m.

The combined power of our access to private barrels will simply be the focal point as we bring wh***ey fans together.

We will be joined by Jonathan Powers who will bring us a special private barrel from their collection and we'll pull one from ours, offering a free sample of each.

We'll be combining our fans for great conversation, community, and wh***ey!

You'll be able to buy our barrels at their stores and drink their barrels at our bar. Win - Win!

So join us Monday October 5th at 7:00 p.m.!

Address

3200 16th Street
San Francisco, CA
94103

Opening Hours

Monday 4pm - 12pm
Tuesday 4pm - 12pm
Wednesday 4pm - 2am
Thursday 4pm - 2am
Friday 4pm - 2am
Saturday 12pm - 2am
Sunday 2pm - 12pm

Telephone

+14155521633

Alerts

Be the first to know and let us send you an email when Elixir posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Establishment

Send a message to Elixir:

Shortcuts

Share

Category