Cantina 76 - Main Street

Cantina 76 - Main Street Casual, independently owned Mexican-inspired taqueria & bar with fresh margaritas, imaginative tacos. and one in downtown Greenville, S.C.
(908)

Cantina 76 is a lively, independently owned restaurant and bar that specializes in fresh Mexican-inspired cuisine and signature margaritas; providing a fast yet satisfying dining experience in a casual, upbeat atmosphere with seating inside and out at two locations in Columbia, S.C. Margaritas are hand-crafted using elements like agave nectar, fresh lime juice and variations such as muddled strawberries and basil. Full of fresh, unique ingredients, the menu includes a large assortment of imaginative tacos, as well as enchiladas, nachos, salads, quesadillas, chimichangas, soups and sides. Sauces, dressings and salsas are made in-house daily, and the bar is stocked with a selection of premium tequilas. This comfortable, inviting restaurant and bar is a go-to for families, couples, young professionals, the business community and college students – perfect for a night out and drinks with friends or a quick meal with coworkers during a lunch break. Cantina 76 was founded in 2009 by four college friends in Columbia, S.C. A popular neighborhood restaurant and bar serving fresh, Mexican-inspired cuisine, Cantina 76 expanded to Columbia’s Main Street in 2013. Its first out-of-town expansion is to ONE City Plaza in downtown Greenville, S.C., in 2016. Metered parking available along Main Street and surrounding blocks. Enjoy half-priced Original House Margaritas during Happy Hour, Monday-Friday, 4-7 p.m. and all-day until 7 p.m. on Saturday; $2 Corona and Corona Light on Friday; and $1 PBR and $1 discount on all other drinks during Happy Hour, Monday-Friday, 4-7 p.m. Tweet, Instagram and Snapchat with us: .

Join us tonight for free tastings of LALO Tequila & Tito’s at 7PM and then Suncrusier at 8PM! See you there!
09/11/2026

Join us tonight for free tastings of LALO Tequila & Tito’s at 7PM and then Suncrusier at 8PM! See you there!

✨ NEW WEEKLY SPECIALS ✨SEPTEMBER 7th - SEPTEMBER 20th🧀 Alabama Brisket Quesadilla ($16.50) – A warm flour tortilla fille...
09/07/2026

✨ NEW WEEKLY SPECIALS ✨
SEPTEMBER 7th - SEPTEMBER 20th

🧀 Alabama Brisket Quesadilla ($16.50) – A warm flour tortilla filled with tender smoked brisket, melted mozzarella, pico de gallo, and topped with house-made Alabama white BBQ sauce.

🍤 Bang Bang Shrimp Taco ($5.50) – Fried shrimp topped with Thai chili aioli, pineapple pico, and a Sriracha drizzle.

🥒 Chef’s Veggie:
Fried pickles with Southwest ranch.

The best kind of Sunday? The one before a Monday off. 🍹🌮➕ALL locations OPEN on Labor Day 11AM - 9PM. ‼️Heads Up -  is cl...
09/06/2026

The best kind of Sunday? The one before a Monday off. 🍹🌮

➕ALL locations OPEN on Labor Day 11AM - 9PM.

‼️Heads Up - is closing early tonight at 8PM, but open regular hours tomorrow.

Welcome back, students! Capital City Kickoff Weekend is here! 🌮🍹August 27–29, college students can show a valid Carolina...
08/28/2026

Welcome back, students! Capital City Kickoff Weekend is here! 🌮🍹

August 27–29, college students can show a valid Carolina ID or student ID from any Columbia-area college to enjoy this special exclusively at our Main Street and Devine Street locations:

🌮 $11 Student Special
Two regular-menu tacos + your choice of queso or salsa, served with chips!

Students 21+ can also enjoy these drink specials:

🍹 Friday, August 28 | 4–7 PM
$5 Original House Margaritas
$20 Original House Margarita Pitchers
$5 Red or White Sangria
$3.50 Corona & Corona Light

🍹 Saturday, August 29 | 11 AM–7 PM
$5 Original House Margaritas
$20 Original House Margarita Pitchers

Grab your friends, bring your student ID, and kick off the school year with tacos and margaritas at Cantina 76! Please drink responsibly. 🌮🎉

✨ NEW WEEKLY SPECIALS ✨AUGUST 24TH - SEPTEMBER 6TH🍋 Lemon Garlic Chicken ($4.50) – Seared Chicken topped with lettuce, t...
08/25/2026

✨ NEW WEEKLY SPECIALS ✨
AUGUST 24TH - SEPTEMBER 6TH

🍋 Lemon Garlic Chicken ($4.50) – Seared Chicken topped with lettuce, tomato, and Lemon Garlic Aioli

🍅 Bruschetta Chicken ($4.50) – seared chicken topped with mozzarella cheese, balsamic glaze, and bruschetta

🥬 Chef’s Veggie – Fried Artichokes with Lemon Garlic aioli

✨ NEW Weekly Specials ✨July 27th - August 9th🌮 Devine Carnitas Crunch Taco ($6)A Grilled Flour Tortilla with Refried Bla...
07/27/2026

✨ NEW Weekly Specials ✨
July 27th - August 9th

🌮 Devine Carnitas Crunch Taco ($6)
A Grilled Flour Tortilla with Refried Black Beans and a Crispy Corn Taco Shell, Filled with Marinated Pork, Jalapeño Lime Aioli, Pico de Gallo, and Served with a Lime Garnish.

🤠 Main St. Steak and Cowboy Caviar Taco ($6)
Tender Steak Topped with Chipotle Crema, Cowboy Caviar, Cotija Cheese and Served with a Lime Garnish.

🫘 Chef’s Veggie:
Cowboy Caviar Served with Warm Corn Chips

🌵 Happy National Tequila Day!Whether you’re loyal to the Original House Margarita or trying one of our signature tequila...
07/24/2026

🌵 Happy National Tequila Day!

Whether you’re loyal to the Original House Margarita or trying one of our signature tequila cocktails, today is the perfect excuse to raise a glass. Pair it with your favorite tacos, grab your crew, and celebrate with us at Cantina 76. Cheers! 🍹

🍹We’re shaking things up at the Columbia Margarita Festival this weekend!Join us Saturday, July 25 from 12–6 PM at Savag...
07/21/2026

🍹We’re shaking things up at the Columbia Margarita Festival this weekend!

Join us Saturday, July 25 from 12–6 PM at Savage Craft Ale Works as Cantina 76 competes for the title of Best Margarita! 🏆

Your ticket includes 10 margarita tastings from local restaurants and bars, plus you’ll get to vote for your favorite (we hope it’s us 😉).

Expect an afternoon of:
✨ Margarita tastings
🎶 Live DJs
🌮 Street food
🛍️ Local vendors
🍺 B**r garden
🇲🇽 Raffle for a trip to Mexico

Come sip, vote, and help us bring the Best Margarita title home to Cantina 76! 🎉
*Please drink responsibly
*DO NOT drink & drive - Use or

📍 Savage Craft Ale Works
📅 Saturday, July 25
⏰ 12:00 PM – 6:00 PM
Link in BIO to purchase tickets & use code 5OFFMARGS to get $5 off your tickets

columbiasc

⭐️ NEW Weekly Specials ⭐️July 13th -July 26th🍑 Kiawah Peach Steak Taco ($6)Marinated Steak, Rio Peach Salsa with Tajin, ...
07/14/2026

⭐️ NEW Weekly Specials ⭐️
July 13th -July 26th

🍑 Kiawah Peach Steak Taco ($6)
Marinated Steak, Rio Peach Salsa with Tajin, and topped with cilantro

🌽 Main St. Steak Elote Taco ($6)
Tender grilled steak served with our take on Mexican street corn—a chilled elote salad—and garnished with a fresh lime wedge.

🫛 Chef’s Veggie:
Lightly fried okra with southwest ranch dressing.

Join us tonight for First Thursday on Main starting at 4PM!!
07/02/2026

Join us tonight for First Thursday on Main starting at 4PM!!

Address

1301 Main Street
Columbia, SC
29201

Opening Hours

Tuesday 11am - 9pm
Wednesday 11am - 9pm
Thursday 11am - 10pm
Friday 11am - 10pm
Saturday 11am - 10pm

Alerts

Be the first to know and let us send you an email when Cantina 76 - Main Street posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Shortcuts

Share