Cantina 76 - Main Street

Cantina 76 - Main Street Casual, independently owned Mexican-inspired taqueria & bar with fresh margaritas, imaginative tacos. and one in downtown Greenville, S.C.
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Cantina 76 is a lively, independently owned restaurant and bar that specializes in fresh Mexican-inspired cuisine and signature margaritas; providing a fast yet satisfying dining experience in a casual, upbeat atmosphere with seating inside and out at two locations in Columbia, S.C. Margaritas are hand-crafted using elements like agave nectar, fresh lime juice and variations such as muddled strawb

erries and basil. Full of fresh, unique ingredients, the menu includes a large assortment of imaginative tacos, as well as enchiladas, nachos, salads, quesadillas, chimichangas, soups and sides. Sauces, dressings and salsas are made in-house daily, and the bar is stocked with a selection of premium tequilas. This comfortable, inviting restaurant and bar is a go-to for families, couples, young professionals, the business community and college students – perfect for a night out and drinks with friends or a quick meal with coworkers during a lunch break. Cantina 76 was founded in 2009 by four college friends in Columbia, S.C. A popular neighborhood restaurant and bar serving fresh, Mexican-inspired cuisine, Cantina 76 expanded to Columbia’s Main Street in 2013. Its first out-of-town expansion is to ONE City Plaza in downtown Greenville, S.C., in 2016. Metered parking available along Main Street and surrounding blocks. Enjoy half-priced Original House Margaritas during Happy Hour, Monday-Friday, 4-7 p.m. and all-day until 7 p.m. on Saturday; $2 Corona and Corona Light on Friday; and $1 PBR and $1 discount on all other drinks during Happy Hour, Monday-Friday, 4-7 p.m. Tweet, Instagram and Snapchat with us: .

🌊 Sip into something special tonight at Cantina 76 Main Street!We’re teaming up with Gray Whale Spirits for an evening o...
06/10/2026

🌊 Sip into something special tonight at Cantina 76 Main Street!

We’re teaming up with Gray Whale Spirits for an evening of complimentary tastings from 5:30 PM–7:30 PM.

Try:
🍇 Gray Whale Vodka in a refreshing Transfusion
🍋 Gray Whale Gin in a crisp Gin & Tonic

Whether you’re a gin lover, vodka fan, or just looking for a great way to start your evening, we’ve got you covered.

📍 Cantina 76 Main Street
⏰ 5:30 PM–7:30 PM

Tag your tasting buddy and meet us at the bar! Reminder, please drink responsibly. Don’t drink & drive.

✨ NEW HAPPY HOUR FOOD DROP AT CANTINA 76 - MAIN✨We’ve got fresh flavors hitting this location, and trust us—you’ll want ...
06/09/2026

✨ NEW HAPPY HOUR FOOD DROP AT CANTINA 76 - MAIN✨

We’ve got fresh flavors hitting this location, and trust us—you’ll want to clock out early for these.

📍 Main Street
Cuban Roll Up – $12
2 Tacos & Queso or Salsa – $11
$3 Off All Quesadillas

⏰ Monday–Friday | 3PM–6PM | Dine-In Only

Make happy hour the best part of your day. 🍹🌮

05/25/2026
✨ NEW WEEKLY SPECIALS ✨May 18th - May 31st 🥩 Brisket Quesadilla - $18Flour tortilla stuffed with smoked brisket, pico de...
05/19/2026

✨ NEW WEEKLY SPECIALS ✨
May 18th - May 31st

🥩 Brisket Quesadilla - $18
Flour tortilla stuffed with smoked brisket, pico de Gallo, and drizzled with our home made Alabama white sauce.

🍤 Buffalo Shrimp Taco - $5.50
Fried shrimp covered in our home made buffalo sauce and then topped with lettuce & pico de gallo

🌽 Chef’s Veggie:
Sweet corn nuggets served with southwest ranch

Sundays are for margaritas 🍹Starting now, every Sunday at Cantina 76 Main Street:🔥 $2 OFF Los Sundays Margaritas• Blanco...
05/17/2026

Sundays are for margaritas 🍹

Starting now, every Sunday at Cantina 76 Main Street:
🔥 $2 OFF Los Sundays Margaritas
• Blanco
• Reposado
• Jalapeño

AND sip on our Original House Marg specials for just $6.76:
• Mi Campo OH Marg
• Camarena Blanco OH Marg

Because weekends should always end with tacos & tequila 😎

Your Thursday after-work plans just made themselves  👌Happy Hour at Cantina 76 — Monday–Friday | 3–6 PM | Dine-In Only🍔 ...
05/14/2026

Your Thursday after-work plans just made themselves 👌

Happy Hour at Cantina 76 — Monday–Friday | 3–6 PM | Dine-In Only

🍔 Double Stacked Bacon Cheddar Burger Quesadilla — $12
🌮 Any 2 tacos + salsa or queso — $11
🧀 $3 off entrée quesadillas

Come hungry. Leave happy. 🌮

🎓🥂 Graduation weekend is here, and we’re raising a glass to our amazing Cantina 76 grads — Kaylee, Kaitlyn, Stephanie, M...
05/08/2026

🎓🥂 Graduation weekend is here, and we’re raising a glass to our amazing Cantina 76 grads — Kaylee, Kaitlyn, Stephanie, Morgan, Amber, Savannah, Lydia, Evan, and Kristin! We are so proud of everything you’ve accomplished and grateful to have you as part of the Cantina 76 family. Congrats, grads! ❤️🖤

Tonight we’ll also have FREE tastings of Garnet & Black Vodka drinks specials by & that directly supports Gamecock Athletes:
📍 Main Street: 4:30PM–5:30PM
📍 Devine Street: 6PM–7PM

To all graduates — Celebrate with our Graduation Drink Specials available at BOTH Main Street & Devine Street locations:

🍹 Gamecock Margarita
🍸 Sandstorm Spritz with Garnet & Black Vodka
🥃 Fighting Gamecock Mule with Garnet & Black Vodka
🍺 Plus Lime Drop Lager from

Both locations are OPEN today from 11AM–10PM!
✨ Tables are first come, first serve — come celebrate with us! 🎉

🌮 NEW WEEKLY SPECIALS (May 4th –17th):�🔥 Fiesta Steak Taco – Seared Sirloin, Jalapeño-Lime Aioli, Sriracha, Cotija, and ...
05/07/2026

🌮 NEW WEEKLY SPECIALS (May 4th –17th):
�🔥 Fiesta Steak Taco – Seared Sirloin, Jalapeño-Lime Aioli, Sriracha, Cotija, and topped with Fried Onions
�🔥 Baja Fish Taco – Fried Cod, Jalapeño-Lime Aioli, and topped Pico de Gallo served with a lime wedge
�🔥 Chef’s Veggie – Fried Okra & Southwest Ranch

🎉 Cinco Days of Cinco de Mayo at Cantina 76 🌮🍹Why celebrate for one day when you can party for FIVE? Join us May 1–5 at ...
05/01/2026

🎉 Cinco Days of Cinco de Mayo at Cantina 76 🌮🍹

Why celebrate for one day when you can party for FIVE? Join us May 1–5 at BOTH Devine Street & Main Street for nonstop fiesta vibes—live music, tequila tastings, drink specials, and more all week long. 🎶🔥

Featuring tequila favorites like Patron, Casamigos, Codigo, Don Julio, Teremana, Mi Campo, Espolon, Del Maguey, Cazadores, Camarena & Astral 🥃

📍 MAIN STREET

May 1 – DJ + Patron 🎧
DJ Mason Davis (6–9PM) + Patron Barrel Select tastings & swag

May 2 – Live Music 🎶
Will Spainhour (6–9PM) + Cazadores, Camarena & more tastings

May 3 – Sunday FUNDAY 🌮
Allison Skipper (5–8PM)
🥃 Los Sundays tasting (12–2PM)
🔥 Illegal Mezcal features ALL NIGHT

May 4 – Live Music + Teremana 🎤
Neighbor’s Worst Nightmare (5–8PM) + Teremana tastings

May 5 – CINCO FINALE 🎉
Lola Grace (6–9PM)
🚲 Patron Blender Bikes (6PM) + giveaways
🍹 Margarita specials (keep the cup 👀)
Happy Hour 4-7PM with Food & Drink Specials — Look here: www.cantina76.com/mainstreet

ONLY AT MAIN — GRAB A CINCO STAMP CARD, GET IT STAMPED ALL 5 DAYS AT MAIN & EARN A $20 GIFT CARD ON MAY 5TH!

🎉 ALL WEEK LONG (BOTH LOCATIONS)
⏰ Happy Hour Specials
🌮 Food specials
🎁 Swag, giveaways & tastings daily

Two locations. Five days. Endless tequila. 🍹🔥
Hit Main. Hit Devine. Or do both. 😎

April is full of reasons to celebrate—13 of them, to be exact! 🎉 Shoutout to our amazing team members marking their work...
04/29/2026

April is full of reasons to celebrate—13 of them, to be exact! 🎉 Shoutout to our amazing team members marking their work anniversaries this month at Cantina 76. Your dedication and drive make all the difference every single day. We’re lucky to have you on this journey with us! 🌮✨

Address

1301 Main Street
Columbia, SC
29201

Opening Hours

Tuesday 11am - 9pm
Wednesday 11am - 9pm
Thursday 11am - 10pm
Friday 11am - 10pm
Saturday 11am - 10pm

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